Revolutionary Treatment for Peritoneal Carcinomatosis
PIPAC (pressurized intraperitoneal aerosol chemotherapy) is a new development in the treatment of cancer, presenting a ray of hope to patients who develop peritoneal carcinomatosis. This new non-invasive process offers a successful solution to conventional HIPEC (hyperthermic intraperitoneal chemotherapy) treatment of patients with peritoneum-derived lesions due to different oncological disorders.
Understanding PIPAC Technology
PIPAC represents an innovative treatment technique that administers chemotherapy to the area of the peritoneal cavity in the form of a pressurized aerosol. This specific treatment mechanism enables the best possible distribution of the drug in the abdominal cavity, and at the same time, there is minimal systemic exposure and related side effects.
The process involves using micropump technology to turn liquid chemotherapy into a fine aerosol mist so it can be more peritoneally penetrating than ever before. The featured innovation of the delivery system is a big step in the treatment of intraperitoneal cancer since it is precise and effective in ways that could not be achieved before.
The PIPAC Procedure: How It Works
PIPAC is conducted with the help of a fully furnished operating room, in which a patient gets full anesthetic assistance and remains comfortable inside the room to pass a sufficient period of treatment. Compared to traditional surgical methods, the procedure is a lot less invasive, as it places a small incision into the anterior abdominal wall.
A low-dose solution of cytotoxic is given to the abdomen with a calculated dosage during the treatment. This dose is comparatively low (10-20 percent) of most recommended doses of treatment and plays down the systemic toxicity risk while preserving treatment efficiency. The solution is then administered with exactness through a complex micropump unit whereby the liquid medicine is changed into an aerosol condition.
The distribution of the aerosol evenly over the peritoneum is then done at high pressure levels that promote active tissue penetration of drugs. Such a pressurized type of environment directs the chemotherapy equipment to infiltrate even the most difficult parts of the peritoneal cavity.
The treatment lasts 30 minutes, and the procedure is finalized by the careful removal of the solution with the help of suction.
Chemotherapy drugs are selected individually depending on the nature of the cancer under treatment. Sometimes, there are complementary drugs that are applied as a combination or at the same time to ensure that the highest response is achieved.
Key Advantages of PIPAC Treatment
PIPAC has many benefits compared to conventional therapeutic approaches, so it is appealing to be used by patients with peritoneal carcinomatosis:
- Equal Distribution of Chemotherapy: The aerosol delivery system delivers an equal distribution of chemotherapy across the full abdominal cavity, including some parts that are harder to reach traditionally.
- Increased Tissue Penetration: Strong pressure surroundings enable intraperitoneal tissues to penetrate deep into the drug, enhancing the effectiveness of treatment in the cells.
- Decreased Toxicity: The low-dose strategy substantially reduces treatment-related toxicity and shows equal therapeutic effects, so patients have a greater tolerance and life quality.
- Resistant Cancers: PIPAC using drugs based on platinum has proven very effective even in cases of platinum-resistant diseases, giving hope to patients where treatments fail.
- Systemic Therapy Compatibility: The method can be effectively integrated with systemic chemotherapy so that broad treatment solutions directed at patient-specific activities can be achieved.
The procedure has good safety protocols and low side effects because the drugs do not circulate in the systemic bloodstream. The hemoperitoneal barrier helps to eliminate cytotoxic drug absorption; thus, the patients do not suffer any systemic complications.
PIPAC vs. HIPEC: A Comparative Analysis
As PIPAC is a relatively new treatment, people have been using HIPEC to treat peritoneal carcinomatosis ever since. But, because of a few significant benefits of PIPAC, it is now proving to be the best treatment for a lot of patients.
HIPEC is an established therapy that has been heavily researched and requires a massive accumulation of cytoreductive surgery, and it can be used in the patient only once. The surgical treatment requires a long cut along the full length of the anterior abdominal wall, which causes severe pain and a longer healing process.
PIPAC, on the other hand, is safer, less invasive, and generally far more tolerated by the patient.
PIPAC has a low-invasive approach, and this means that the patient does not need a large surgical incision, and the recovery process is much faster. Unlike HIPEC, PIPAC does not necessitate preoperative cytoreductive surgery, which is why this intervention could be available to patients who are not surgical candidates. Repeatability is one of the greatest strengths of PIPAC. HIPEC treatment can be done once, but
PIPAC treatments may be done several times, which enables continuous treatment of the condition. This treatment power is miraculous, where some patients have found cancer retreat and have found it possible to operate on some cancer constrictions that were initially unreachable.
Treatment Accessibility and Patient Care
PIPAC treatment in patients with small intestine involvement or end-stage peritoneal carcinomatosis is especially good, which normally excludes patients from HIPEC treatment. This widening accessibility implies that more patients can be treated successfully with effective intraperitoneal chemotherapy.
The least invasive procedure with outstanding tolerance issues implies that the procedure is appropriate to be offered to patients who are not prospective candidates for more aggressive treatments. Repeatability of the treatments also permits long-term management by being able to accommodate patient changes in condition and response to treatment.
Contact Information and Consultation
For patients interested in learning more about PIPAC treatment or scheduling a consultation, our experienced medical team is available to provide comprehensive information and personalized treatment recommendations.
Consultation Hours:
- Monday to Saturday: 9:00 AM – 5:00 PM
- Sunday: Video Call Consultation (with prior appointment)
Book Your Appointment: Phone: +91-8218819398
Our top-level employees are focused on delivering outstanding treatment services to patients and making sure that every single patient is offered the very best treatment regimen according to the condition. To fulfill patient needs depending on their preferences and situations, we provide both face-to-face and video consultations.
PIPAC is a revolutionary step in the treatment of cancer, and it gives patients some hope and better results in cases of peritoneal carcinomatosis. Write to us now to know more about how this innovative treatment can be useful to you or your loved ones.
